I have used this with great results, from DR. William Kelly Nutritional-Metabolic Therapy
Coffee Enemas
As at second aid in detoxification, Kelley advised all his patients to take at least one coffee enema daily. His reasoning was that coffee enemas clean out the liver and gallbladder and help the body get rid of the toxins produced during tumor breakdown. During a coffee enema, claimed Kelley, the caffeine that is rapidly absorbed in the large intestine flows quickly into the liver. He held that in high enough concentrations, caffeine causes the liver and gallbladder to contract vigorously, releasing large amounts of stored wastes into the intestinal tract and greatly aiding elimination. Kelley also believed that enemas are important in stimulating the immune system, since most waste products eliminated by detoxification are enzyme inhibitors. Frequent enemas prevent the suppression of protein-digesting enzymes. These enzymes can break down the cancer cells' fibrin (protein) coats, making the cancer cells more vulnerable to the immune system.
Nonorthodox doctors other than Kelley, among them Dr. Max Gerson, have recommended coffee enemas.