TOPIC:

Hi! : )
Does anyone know of any info about if MMS1 might influence vitamin B12 absorption, in any way? By killing the bacteria that we have in the gut and produce a small amount of B12 or any other mechanism?

B 12 requires intrinsic factor to be absorbed, if it's swallowed. Intrinsic factor is a glycoprotein, not a bacteria - so it should not be a problem. If you have a concern, then take the sublingual form, which goes directly to the liver from the mouth and doesn't deal with the stomach.

injecting B12 is really the best/most viable way, most of the studies/research I have found state the sublingual method does not really work....

you can get the shots very cheaply in the U.S. (no prescription required)

www.trimnutrition.com/vitamin-injections/b12-injections.html

(no affiliation with the company, not spamming)

I think it's good to try both. I had the shot and it worked great. Then I started taking 5000 mcg sublingually and got the same effect for a lot less money.

larrymagee wrote:

I think it's good to try both. I had the shot and it worked great. Then I started taking 5000 mcg sublingually and got the same effect for a lot less money.

I suspect you are seeing benefits from oral use of B12, versus sublingual

www.livestrong.com/article/289321-sublingual-vitamin-b12-vs-injectable-b12/

"Sublingual B12

Sublingual B12 products are nonprescription lozenges or tablets that you place under your tongue until they dissolve. Manufacturers of these products claim that taking B12 in this way allows you to avoid the absorption problems associated with oral B12 and get more effective active doses of the vitamin. However, current evidence does not support these claims, and sublingual B12 appears to have the same effectiveness as oral versions of the vitamin, reports the NIH Office of Dietary Supplements."

Hi rb - it's a sublingual tablet from Wonder Laboratories.

larrymagee wrote:

Hi rb - it's a sublingual tablet from Wonder Laboratories.

hey,

not knocking B12, and I am very happy its working for you, just some of my own research leads me to think B12 is to large of a molecule to pass through sublingually....

the effects you are seeing, is likely from oral administration (Again, this is my own conclusion, etc)

I am very happy it is working for you...

if my theory is correct, then you must have adequate intrinsic factor... to make B12 viable for you...

again, this is my own research/conclusion

I have had gastric bypass surgery. It was done in 2002. I have no access to intrinsic factor, period. I am obviously utilizing the sublingual b-12s that I take, or I would be WELL into pernicious anemia at this point.

pam wrote:

I have had gastric bypass surgery. It was done in 2002. I have no access to intrinsic factor, period. I am obviously utilizing the sublingual b-12s that I take, or I would be WELL into pernicious anemia at this point.

looks like 36% of bypass patients do not produce I.F.

Absence of luminal intrinsic factor after gastric bypass surgery for morbid obesity.

Marcuard SP, Sinar DR, Swanson MS, Silverman JF, Levine JS.


Source

Department of Medicine, East Carolina University, School of Medicine, Greenville, North Carolina 27858-4354.


Abstract


Abnormally low serum cobalamin levels (less than 180 pg/ml) have been observed in 154 of 429 patients (36%) at an average of 22 months (range 3-64 months) after gastric bypass surgery for morbid obesity. Twenty-four patients underwent a Schilling test and retrograde endoscopy of the bypassed gastric segment to determine the presence of intrinsic factor (IF) in gastric aspirates and in mucosal biopsies at 22 +/- 4 months after surgery. Five patients had a normal cobalamin level (405 +/- 44 pg/ml), and gastric juice intrinsic factor was present in three of them (11 +/- 7 ng/ml). Nineteen patients had a low cobalamin level (113 +/- 8 pg/ml), and gastric juice IF was found in only two subjects of this group (10 ng/ml each). Basal gastric juice IF concentration of healthy control subjects was 24 +/- 5 ng/ml. Schilling test results were normal in all five patients of the first group and in only nine patients of the group with cobalamin deficiency after surgery. To assess whether IF was present within the parietal cells of subjects with absent luminal IF, we studied gastric biopsy material of 14 patients using a well-characterized indirect immunoperoxidase method. IF was identified in fundic mucosal biopsy specimens of all 14 patients with absent gastric juice IF. We conclude that cobalamin deficiency occurs in a significant number of patients after gastric bypass and is associated with absence of gastric juice IF. We propose that this abnormality might be caused by inadequate secretion of IF from the bypassed stomach.


www.ncbi.nlm.nih.gov/pubmed/2666054