If they are having leg pain at night its a healing crisis caused by the DMSO (methylated sulfur) causing too much toxic circulation. Id get them to up their sulfate using Epsom for a while, then back way (way!) down on the DMSO and see how it goes.
I'm looking for something better than Epsom, if something exists, (maybe like to old "sulfur pills" of the 1960's and 70's) to replace Epsom that would do the same thing as the sulfate in Epsom, but without the bowl tolerance limiting factor that the Magnesium causes. For now, Epsom is the solution. Get their sulfur up by getting them oral Epsom USP and that will allow their body to help the MMS work better and it wont give them a healing crisis (leg pain, etc..).
Epsom is also the treatment for that leg pain if they do get into a healing crisis. I learned that this morning on myself and my sick wife. I'm learning really fast!
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