You can premix and keep in the fridge overnight as long as the lid on the bottle is tight. I'd go with Jim's current book - Master Mineral Solultion of the Third Millennium. It builds on the earlier ones, but has more current changes. The question becomes, do you want to do the ebook or do you want the hard copy. IF IT WERE ME, and I am comfortable with ebooks (which come in PDF files) - I'd get the ebook, because they're easier to search with keywords. Hard copies you can write in - however, I know that Jim is working on a second edition of the book, so, you may prefer to get the ebook now and the hard copy after the 2nd edition comes out.
Not sure where you're getting your information on acidophilus - that might help to understand - MMS should not interfere with acidophilus - I would take the minerals at night, 2 hrs after your last dose - calcium/mag/posassium. etc. - those types of minerals. Unless you are doing ocean water - the minerals in ocean water are a can be taken prior to the first dose, by about an hour.
